Testicular cancer
What is Testicular Cancer
THE PROBLEM
Testicular cancer, the most common cancer in younger men aged between 15 and 45, and the rate is increasing. There are nearly 2,000 cases per year, but it is relatively rare compared to cancers such as lung or breast cancer. The most common way this cancer is identified is by finding a lump in the testicle. Therefore, men falling into this age group should be encouraged to examine their testicles for lumps on a regular basis. Recent surveys suggest that many men are unaware of testicular cancer or prefer to ignore it, and that few men check their testicles.
In over 25% of cases, the cancer has already spread by the time of diagnosis. Despite this, today more than 95% of patients are cured with chemotherapy. If caught at an early stage, the probability of a successful cure is more than 98% with the treatment being much simpler and may only require surgery to the diseased testicle.
The testicles are two small oval shaped organs (they can also be called testes or gonads), and are the male sex glands. They are located behind the penis in a pouch of skin called the scrotum. The testicles produce sperm and testosterone. The testicles are located outside the body because sperm develop best at a temperature several degrees cooler than normal internal body temperature.
The germ cells inside the seminiferous tubules create sperm. The sperm move into the epididymis where they mature. They are stored there for a few weeks until they eventually move up the vas deferens to combine with fluids from the prostate and seminal vesicles to form what you normally think of as semen. The whole process takes about seven weeks.

The leydig cells distributed throughout the testicle are the body's main source of testosterone. Testosterone, the male sex hormone, is essential to the development of the reproductive organs and other male characteristics such as:
- Body and facial hair
- Low voice
- Muscle development
- The ability to have an erection
- Sex drive (libido)
Without enough testosterone, a man may lose his sex drive and suffer from fatigue, depression, hot flushes and osteoporosis (thinning of the bones).
POSSIBLE RISK FACTORS
Unlike many cancers, there are few known strong risk factors for testicular cancer, and we cannot currently predict who is likely to get the disease (unlike the link between lung cancer and smoking). While most of these cancers occur in unsuspecting individuals, some risk factors can be traced in a minority of cases. These include:
- Men born with an undescended testicle or where the testicle fails to descend into the scrotum. Research has shown the risk of testicular cancer increases dramatically if this is not corrected by the age of 11
- A brother/father with testicular cancer
- A previous history of testicular cancer
- A sedentary life style increases, the risk but regular exercise reduces risk
- Mumps (a rare complication called mumps orchitis) may have an increased risk
- Repeated trauma (rather than inevitable knocks) increases risk
- Men with HIV have a slightly higher incidence of testicular cancer, for more information please follow this link.
- A recent study has shown a correlation between smoking marijuana and an increased risk of testicular cancer
Orchid is extremely grateful to the Bernard Sunley Charitable Foundation for its support towards the testicular cancer areas of this website